8-425 Open Top Screw Closures Pre-Slit

8-425 Open Top Screw Closures with Pre-Slit PTFE/Silicone Septa:

Precision Sealing for 2mL Autosampler Vials in HPLC & GC Analysis
The 8-425 Open Top Screw Closures with Pre-Slit Septa are expertly designed for use with 2mL 8-425 threaded autosampler vials, providing a high-integrity seal and reliable performance in demanding analytical applications. Constructed with premium-grade materials, each closure features a chemically resistant PTFE/Silicone pre-slit septum, ensuring excellent resealability, leak-proof protection, and minimal sample interaction.

These closures are ideal for high-precision chromatographic testing, including high-performance liquid chromatography (HPLC) and gas chromatography (GC). The pre-slit design allows direct penetration by autosampler needles without coring, preserving septa integrity over multiple uses.

Key Features and Benefits

• High-Quality Material Composition
  Manufactured with PTFE-lined silicone septa and chemically resistant screw-thread caps, offering exceptional durability and broad chemical compatibility.

• Precision Fit for 2mL 8-425 Vials
  Engineered to match 8-425 threaded autosampler vials perfectly, ensuring airtight seals that prevent evaporation, contamination, or sample loss.

• Pre-Slit Septa for Autosampler Access
  The pre-slit design allows direct needle penetration without manual cap removal, making it ideal for automated, high-throughput workflows.

• Minimized Sample Contamination
  Leak-resistant and inert, the materials prevent chemical interaction with sensitive analytes—preserving sample integrity and accurate results.

• Compatible with HPLC and GC Systems
  Supports a wide range of applications in analytical chemistry, pharmaceutical labs, environmental monitoring, and quality control testing.

• Easy to Use
  Simple screw-cap design ensures quick, secure application and removal, reducing handling time in busy lab environments.

Applications

The 8-425 Open Top Screw Closures with Pre-Slit Septa are ideal for:

• High-throughput HPLC and GC autosampler analysis

• Sample handling in clinical, pharmaceutical, and environmental laboratories

• Automation-compatible workflows requiring non-invasive sampling

• Minimizing contamination and ensuring repeatable testing results

For labs where accuracy, consistency, and reliability are essential, these closures deliver the perfect balance of performance, protection, and ease of use.