ARACUS “advanced” Amino Acid Analyzer


The ARACUS “Advanced” Amino Acid Analyzer enhances the ARACUS “Classic” with a second pump drive, enabling independent fluidic control for eluents and reagents. This improves the signal-to-noise ratio and allows flexible parameter adjustments, including the use of OPA (o-phthalaldehyde) with a fluorescence detector for primary amine detection.

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The ARACUS “advanced” Amino Acid Analyzer by membraPure GmbH is a next-generation analytical system designed for high-throughput, precise amino acid quantification across diverse sample types. Building on the reliability of the ARACUS “classic”, the “advanced” model integrates automated sample injection, optimized ion-exchange chromatography, and dual-wavelength photometric detection, ensuring superior performance in routine and research-based amino acid analysis. This system uses post-column derivatization with ninhydrin, the gold standard in amino acid detection, offering exceptional sensitivity and reproducibility. The ARACUS “advanced” is equipped with a powerful autosampler (up to 120 samples) and customizable methods for physiological, food/feed, and pharmaceutical applications. It’s ideal for laboratories demanding high accuracy, throughput, and regulatory compliance (e.g., GLP, ISO, FDA environments). With intelligent software (ChromStar ARACUS), user-friendly interface, and data integrity features, the ARACUS “advanced” stands out as a robust solution for both routine and specialized amino acid testing.

Technical Specifications of ARACUS “advanced” Amino Acid Analyzer

Method

  • post column derivatization with Ninhydrin

Autosampler

  • 2 racks, each of them with space for 48 vials, sample cooling dosage in 3 different injection modes: full loop (100 μL), partial loop (5 – 50 μL), microliter pickup (1 – 35 μL)

Column

  • stainless steel, cation exchange resin reproducibility of retention time <1  % RSD, reproducibility of peak area < 3.0 % RSD

Column Oven

  • 20 – 100 °C, accuracy 0.1 %

Reactor Temperature

  • 20 – 140 °C

Spectroscopic detection

  • measuring range: high, low LED photometers (440 nm + 570 nm), 8 years warranty, flow cell: 10 μL volume, 3 years warranty

Detection limit

  • < 40 pmol / 20 µL with Ninhydrin, < 4 pmol / 20 µL with OPA

Quantification limit

  • > 100 pmol / 20 µL with Ninhydrin, > 10 pmol / 20 µL with OPA

Pump system

  • dual pump reproducibility of low rate: 0.1 % RSD at 100 μL/min, max. pressure: 400 bar | flow rate: 0.01 – 10.00 mL/min

Maximum operating pressure

  • 120 bar

Ready to use kits

  • kits including eluents, reagent and additional dilution buffer, ammonia absorber and separation columns for 500 – 1000 runs

Columns & Eluents

  • Compatible with all columns, operating with all eluents based on different ionic strength (Li, Na, K)

Control software & Data acquisition

  • Clarity (21 CFR part 11 compliant) or AminoPeak

Power

  • 110 – 230 V

Dimensions

  • 1000 mm x 680 mm x 360mm

Weight

  • 60 kg
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