IONUS Post Colum Derivatization (PCD)

The IONUS Ion Analyzer with Post Column Derivatization (PCD) is a specialized version of membraPure’s IONUS system, designed for highly selective detection of specific analytes that require chemical modification after ion separation. By integrating Post Column Derivatization into the ion chromatography workflow, this system offers enhanced sensitivity and specificity, especially for compounds that are weakly responsive or undetectable via standard conductivity detection. This platform is ideal for trace-level analysis of transition metals, amino acids, sugars, and other complex ions in environmental, clinical, and food safety applications. The PCD module ensures accurate quantification by reacting eluted analytes with colorimetric or fluorometric reagents, producing a measurable signal. It is a modular, fully automated system, with precise temperature control and reaction time management, delivering high reproducibility and low detection limits.

Technical Specifications of IONUS Post Colum Derivatization (PCD)

Method

• ion exchange chromatography with post column derivatization

Manual Injection

• 20 µL, further injection loops upon request (50 µL, 100 µL, 200 µL)

Autosampler

• 2 racks, each of them with space for 48 vials (1.5 mL) or 12 vials (6 mL), sample cooling, loop 100 µL, 3 injection modes (full-loop, partial loop, microliter-pickup)

Column

• stainless steel / PEEK

Thermostat

• ambient + 5 °C up to 50 °C

Detection

• conductivity detector: noise: 0.02 µS/ s | range: 0 – 10 mS/cm effective cell volume: 1 µL

Isocratic Pump System

• max. pressure: 400 bar | flow rate: 0.01 – 10.00 mL/min reproducibility of flow rate: 0.1 % RSD at 100 µL/min

Maximum Operating Pressure

• 120 bar

Control Software & Data Acquisition

• Clarity (21 CFR part 11 compliant) or AminoPeak

Power

• 110 – 230 V, 50/60 Hz

Dimensions

• 1000 mm x 350 mm x 375 mm

Weight

• 60 kg