Pilot-scale Freeze Dryer/ Lyphilizer

A versatile pilot-scale freeze dryer that completely simulates the technical requirements of an industrial freeze dryer. With a compact, well-designed footprint and a wide redundancy range, it conforms to GMP and FDA standards. The main unit—equipped with a WRL controller and a liquid temperature control shelf—allows precise control of both pre-freezing and freeze-drying stages. It supports advanced test systems (such as eutectic point tests, pressure rise/comparison methods for endpoint determination, and freeze-drying curve recording) and can be equipped with engineering WRL control software for direct graphical computer control of the process. Additionally, it can be configured with H₂O₂ sterilization, high-pressure steam sterilization, or an integrated glove box system for clean room operation. The cold trap and freeze-drying chamber are constructed with 316L stainless steel to ensure chamber cleanliness and optimal vacuum performance.

Refrigeration Series

• Dual Compressors:

  • Secop special compressors with air cooling (water cooling system available as an option).

• Refrigeration Method:

  • Cascade refrigeration for high cooling efficiency and reliability using CFC-free, environmentally friendly refrigerants.

• Silicone Oil System:

  • Conducts heat with uniform temperature; accuracy up to 0.1°C.

  • Wide operating range from –100°C to +600°C.

• Independent Refrigeration Circuits:

  • The shelf refrigeration system and cold trap refrigeration system operate independently without switching, ensuring a lower and more stable refrigeration temperature.

Vacuum Series

• Vacuum Pump:

  • German Pfeiffer anti-corrosion pump with an anti-oil return function (specifications vary to meet user needs).

  • Pumping rates range from 9 m³/h to 62 m³/h; the ultimate vacuum can reach 2×10⁻³ mbar.

  • Standard oil mist filter included.

• High-Vacuum Stainless Steel Tubes:

  • Used in all vacuum pipelines to prevent leakage and corrosion.

• Double Anti-Oil Return Device:

  • Completely eliminates damage to equipment and samples.

• Automatic Backfill Air Device:

  • Built-in High Efficiency Particulate Air (HEPA) filter ensures complete cleanliness of backfill air.

• Vacuum Stabilization System:

  • Uses a micro-pass vacuum control valve to stabilize the vacuum level during the freeze-drying process, protecting samples from excessive fluctuations.

• Condensed Liquid Collection and Discharge:

  • Automatically collects and discharges condensed liquid following the freeze-drying process.

Control System Characteristics

• Control Options:

  • Automatic and manual modes available.

• Program Storage:

  • Can store at least 100 independent freeze-drying programs, each containing up to 32 segments (customizable per user requirements).

  • Each segment corresponds to a processing stage (pre-freezing, main drying, and post-drying) and includes key parameters such as cycles, shelf temperature, vacuum, and safety pressure.

• Real-Time Recording:

  • All operational data is recorded in real time; freeze-drying curves and data tables are generated at the process end in compliance with relevant standards and regulations.

• Hierarchical Management:

  • Features hierarchical management and usage process tracking with assigned allocation authority.

• Remote System Capabilities:

  • Fully supports 2G/4G/GSM/Wi-Fi connections.

  • Remote viewing of all device data and remote operation.

  • Remote maintenance, fault detection, guidance, training, and system upgrades.

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