UTS NIR Automatic Tablet Testing System

The UTS NIR automatic tablet testing system is a cutting-edge solution that integrates traditional physical parameter testing with advanced analytical technology. It combines the measurement of weight, thickness, diameter, length, and hardness with Fourier Transform Near-Infrared Spectroscopy (FT-NIR analysis) to determine a tablet’s active pharmaceutical ingredient (API) content. This hybrid capability ensures precision and consistency in both routine quality checks and advanced formulation analysis.

Process Analytical Technology (PAT) Integration

The UTS NIR functions as a fully automated Process Analytical Technology (PAT) tool, ideal for both in-line and offline use. Whether installed directly in production lines or used in laboratory settings, the system provides real-time feedback during tablet manufacturing. When connected to a tablet press, it continuously monitors product quality and automatically transmits all test results back to the tablet press system. This allows operators to respond immediately to any deviations, minimizing waste and ensuring consistent product quality.

Advanced FT-NIR Analysis with NIRFlex N-500

The system includes the NIRFlex N-500 FT-NIR transmission spectrometer from Büchi Labortechnik AG, which supports reliable method transfer from lab-scale testing to full production environments. This enables smooth scale-up and eliminates the need to develop separate methods for different stages of the product lifecycle.

Regulatory Compliance

The UTS NIR complies with the standards outlined in both the European Pharmacopoeia and the United States Pharmacopoeia (USP). It is also fully 21 CFR Part 11 compliant, ensuring it meets stringent electronic data integrity and documentation requirements for pharmaceutical production.

Precision Tablet Positioning

Thanks to a patented two-jaw centering mechanism, the UTS NIR offers tablet positioning accuracy of ± 0.1 mm. This precision ensures consistent measurement results, meeting the high standards expected in laboratory testing. Such reliability is essential for applications requiring strict quality control and validation.

Compact and Modular Design

Designed for versatility, the UTS NIR features a compact, modular structure that fits comfortably under tablet chutes from the industry’s most popular tablet press manufacturers. Its space-saving design makes it ideal for both large-scale and small-scale production facilities.

A range of customizable sample collectors is available to suit specific customer requirements, enabling further offline analysis as needed.

Easy Maintenance

Maintenance and cleaning are fast and straightforward. All parts that require cleaning can be easily removed without the need for tools, reducing downtime and simplifying the routine maintenance process. This contributes to higher operational efficiency and reduced production interruptions.

By combining precision engineering, analytical depth, and regulatory compliance, the UTS NIR is a comprehensive solution for modern tablet testing in both laboratory and manufacturing environments.